Table 2.
Disease Characteristics of the Study Subjects
| Comorbidity Variable | Category | N (%) | Number of DRPs | P-value* |
|---|---|---|---|---|
| Mean (SD) | ||||
| Hypertension | Without | 65 (13.24) | 2.66 (1.68) | 0.005 |
| With | 426 (86.76) | 3.41 (1.81) | ||
| Dyslipidemia | Without | 169 (34.42) | 3.20 (1.90) | 0.329 |
| With | 322 (65.58) | 3.37 (1.77) | ||
| Myocardium infarction | Without | 407 (82.89) | 3.19 (1.83) | <0.001 |
| With | 84 (17.11) | 3.88 (1.59) | ||
| Heart failure | Without | 452 (92.06) | 3.21 (1.78) | <0.001 |
| With | 39 (7.94) | 4.46 (1.83) | ||
| Stroke | Without | 475 (96.74) | 3.29 (1.81) | 0.313 |
| With | 16 (3.26) | 3.87 (1.86) | ||
| Chronic obstructive pulmonary disease | Without | 478 (97.35) | 3.31 (1.82) | 0.854 |
| With | 13 (2.65) | 3.31 (1.70) | ||
| Peptic ulcer disease | Without | 486 (98.98) | 3.31 (1.82) | 0.895 |
| With | 5 (1.02) | 3.20 (1.09) | ||
| Liver disease | Without | 484 (98.57) | 3.35 (0.08) | 0.100 |
| With | 7 (1.43) | 4.43 (0.84) | ||
| Chronic kidney disease | Without | 457 (93.08) | 3.27 (1.78) | 0.205 |
| With | 34 (6.92) | 3.82 (2.15) | ||
| Thyroid dysfunction | Without | 441 (89.82) | 3.34 (1.83) | 0.401 |
| With | 50 (10.18) | 3.06 (1.60) | ||
| Asthma | Without | 460 (93.69) | 3.31 (1.83) | 0.803 |
| With | 31 (6.31) | 3.35 (1.62) | ||
| Mean (SD) | Correlation coefficient | |||
| Charlson comorbidity index | 3.85 (0.93) | 0.130 | 0.004 | |
| Estimated 10-year survival (%) | 0.55 (0.24) | −0.130 | 0.004 |
Note: *Statistical significance was set at a 2-sided P<0.05.
Abbreviation: DRPs, drug-related problems.