The burden of non-communicable diseases (NCD) is increasing at an unprecedented rate globally [1,2]. The surge in recent years strains the already weakened health system in low and middle-income countries (LMICs). Such epidemiological transition in most resource-constrained countries occurs under the constrained health system struggling to contain the persistent burden of communicable diseases [3,4] deaths arising from LMICs, calling for immediate locally driven interventions, but with informed policies and intervention to counteract the drivers of such burden.
Although the standard drivers for NCDs are globally known, namely, tobacco use, physical inactivity, the harmful use of alcohol, and unhealthy diets [5]. These risk factors vary from one country and region to another [6,7]. Therefore, the globally and World Health Organization’s (WHO) recognized best buys may not be adequate if not tailored to the locally determined risk factors, local epidemiology, context, and matching the available resources. These differences and lack of comprehensive knowledge of NCD’s risk factors call for country-led research to understand the local epidemiology, use evidence-based interventions, and apply multi-stakeholder approaches to address such a multi-faceted burden [8,9]. Countries need ownership and use of local resources, adequate healthcare financing for chronic diseases, and community-based initiatives that work within the same contexts to ensure sustainability [10,11].
This series presents efforts by countries facing epidemiological transition with the surge of NCDs amid the persistent burden of communicable diseases [12,13,14,15]. The majority of these countries are in low and middle-income brackets [16,17,18,19]. Such countries are making various efforts to contain the unprecedented burden, drawing several lessons from one another in reaching epidemiological control. Some of the initiatives presented in this series are unique and can be adopted with modifications to suit other countries or regions with similar contexts.
Uniquely, three of the papers presented in this series are from Tanzania. The country has a persistent burden of traditional communicable diseases such as HIV at a national prevalence of 4.7% [20], Malaria at a national prevalence of 9% [21], and tuberculosis with an incidence rate of 222 per 100000 of the population [22], maternal and child health challenges with maternal mortality 524 deaths per 100000 [23]. Under such heavy burden of communicable diseases, Tanzania is facing a fact growing burden of NCDs, accounting for 41% of the Disability Adjusted Life Years (DALYs) [24], and NCDs alone accounting for more than 31–34% of premature deaths [25,26]. The burden of NCDs aligns with nutritional, economic, and demographical transitions [27]. Whereas the common risk factors such as unhealthy dietary habits, overweight and obesity, tobacco intake, and excessive alcohol consumption are associated with the big four NCDs in the country, namely: cardiovascular diseases, cancers, chronic respiratory diseases, and diabetes; they account for only 40% of the known risk factors [24]. Furthermore, the burdens of other NCDs, such as road traffic injuries, mental health disorders, and congenital conditions, are also rising and equally demand immediate attention. The confluence of the previous and persistent burden of childhood under nutrition in Tanzania [28,29] may also attribute to the unknown risk factors found elsewhere [30,31]. The high burden of maternal under-nutrition [32] may be behind poor birth outcomes, such as low birth weight, which may in turn explain the rising NCD burden in terms of morbidity and mortality in the country [33]. Understanding the local contextual factors driving the NCDs burden is therefore crucial for any meaningful success.
Strengthening the health system has been a hallmark in efforts to address the local burden in Tanzania [24]. The Government of Tanzania, through the Ministry of Health (MoH), has been working with the Tanzania Non-communicable Diseases Alliance (TANCDA) and Tanzania Diabetes Association (TDA), and other national and international organizations with interest in NCDs, pioneered the development of the National Strategic Plan for NCDs launched in 2009 [34]. The collaboration between government and non-government stakeholders resulted in the development of the National NCDs Control and Prevention Program in 2019 to coordinate the national preventive, curative, and rehabilitative efforts and align the stakeholders [35].
Although the burden is still rising on all NCDs in Tanzania [36], the country is on the right track in NCDs response [37]. Tanzania is far away from having a transformative and resilient health system to cope with the rising cost of health care from such chronic conditions [38,39,40]. The strategies’ implementation and stakeholder collaboration should also emphasize prevention and control measures. The focus on NCD prevention and control heralds the start of a new era in providing affordable health services while maintaining equity and quality health services for those affected by chronic diseases and disabilities for the rest of their lives [40,41].
Through the coordinated efforts, the national NCDs Control and Prevention Program, the national NCDs week was inaugurated to commemorate various efforts addressing the NCDs burden in the country. In this particular week, the MoH coordinates the national NCDs conference serving as a platform to convene scientists in Tanzania and beyond to discuss the burden and national response and innovations to address the new challenges. The NCDs week has advocacy activities, school health promotion, physical activities, and NCDs screening. The week attracts national and civil organizations leaders, a sign of commitment to addressing the burden of NCDs. As explained in these papers, such efforts may inform other countries with similar burdens or contexts in setting up or strengthening their national and sub-countries’ response against the rising burden of NCDs.
Acknowledgements
The authors wish to extend sincere gratitude to the Directorate of Research and Publications of the Muhimbili University and Allied Sciences, the Ministry of Health-National NCD prevention and control program, and collaborating partners; the Non-Communicable Diseases Alliance (TANCDA), Tanzania Diabetes Association (TDA), World Health Organization (WHO), Tanzania Cancer Association (TCA), Tanzania Association for Respiratory Diseases (TARD), Heart Foundation of Tanzania (HFT), DANIDA and World Diabetes Foundation (WDF) for the great efforts put into supporting and implementing NCDs program and activities in the country.
Competing Interests
The authors have no competing interests to declare.
Author contributions
All authors had full access to the data used in this article, and they contributed to either conceptualization, development, data analysis, and/or review of this manuscript.
References
- 1.Chikowore T, Kamiza AB, Oduaran OH, Machipisa T, Fatumo S. Non-communicable diseases pandemic and precision medicine. Is Afr ready? EBioMedicine. 2021; 65: 103260. DOI: 10.1016/j.ebiom.2021.103260 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 2.Global Burden of Noncommunicable Diseases | PRB. Accessed February 19, 2023. https://www.prb.org/resources/global-burden-of-noncommunicable-diseases/.
- 3.Li Z, Shi J, Li N, Wang M, Jin Y, Zheng Z jie. Temporal trends in the burden of non-communicable diseases in countries with the highest malaria burden, 1990–2019: Evaluating the double burden of non-communicable and communicable diseases in epidemiological transition. Global Health. 2022; 18(1): 1–9. DOI: 10.1186/s12992-022-00882-w [DOI] [PMC free article] [PubMed] [Google Scholar]
- 4.Noncommunicable diseases. Accessed February 19, 2023. https://www.who.int/news-room/fact-sheets/detail/noncommunicable-diseases.
- 5.Noncommunicable diseases. Accessed March 2, 2023. https://www.who.int/health-topics/noncommunicable-diseases#tab=tab_1.
- 6.Peters R, Ee N, Peters J, et al. Common risk factors for major noncommunicable disease, a systematic overview of reviews and commentary: The implied potential for targeted risk reduction. Ther Adv Chronic Dis. 2019; 10. DOI: 10.1177/2040622319880392 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 7.Budreviciute A, Damiati S, Sabir DK, et al. Management and prevention strategies for non-communicable diseases (NCDs) and their risk factors. Front Public Health. 2020; 8: 788. DOI: 10.3389/fpubh.2020.574111 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 8.Tanzania Medical Journal. Tanzania Medical Journal. Abstracts presented at the 3rd National Non-Communicable Diseases Scientific Conference at Arusha International Conference Center in Arusha, Tanzania. Tanzania Medical Journal. 2022; 33(2): 1–124. DOI: 10.4314/TMJ.V33I2.569 [DOI] [Google Scholar]
- 9.Tanzania Medical Journal. Proceedings of the Second National Non-Communicable Diseases Scientific Conference 2020. Tanzania Medical Journal. >2021; 32(1): 1–128. DOI: 10.4314/TMJ.V32I1.472 [DOI] [Google Scholar]
- 10.Canfell OJ, Davidson K, Woods L, et al. Precision public health for non-communicable diseases: An emerging strategic roadmap and multinational use cases. Front Public Health. 2022; 10. DOI: 10.3389/fpubh.2022.854525 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 11.Gassner L, Zechmeister-Koss I, Reinsperger I. National strategies for preventing and managing non-communicable diseases in selected countries. Front Public Health. 2022; 10: 131. DOI: 10.3389/fpubh.2022.838051 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 12.Ciccacci F, Orlando S, Majid N, Marazzi C. Epidemiological transition and double burden of diseases in low-income countries: The case of Mozambique. Pan Afr Med J. 2020; 37(49): 1–8. DOI: 10.11604/pamj.2020.37.49.23310 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 13.Bollyky TJ, Templin T, Andridge C, Dieleman JL. Understanding the relationships between noncommunicable diseases, unhealthy lifestyles, and country wealth. Health Aff. 2015; 34(9): 1464–1471. DOI: 10.1377/hlthaff.2015.0343 [DOI] [PubMed] [Google Scholar]
- 14.Bai J, Cui J, Shi F, Yu C. Global epidemiological patterns in the burden of main non-communicable diseases, 1990–2019: Relationships with socio-demographic index. Int J Public Health. 2023; 68: 1–13. DOI: 10.3389/ijph.2023.1605502 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 15.Bollyky TJ, Templin T, Cohen M, Dieleman JL. Lower-income countries that face the most rapid shift in noncommunicable disease burden are also the least prepared. Health Aff. 2017; 36(11): 1866–1875. DOI: 10.1377/hlthaff.2017.0708 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 16.Miranda JJ, Kinra S, Casas JP, Davey Smith G, Ebrahim S. Non-communicable diseases in low- and middle-income countries: Context, determinants and health policy. Trop Med Int Health. 2008; 13(10): 1225. DOI: 10.1111/j.1365-3156.2008.02116.x [DOI] [PMC free article] [PubMed] [Google Scholar]
- 17.Ndubuisi NE. Noncommunicable diseases prevention in low- and middle-income countries: An overview of health in all policies (HiAP). Inquiry. 2021; 58: 1–6. DOI: 10.1177/0046958020927885 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 18.Bigna JJ, Noubiap JJ. The rising burden of non-communicable diseases in sub-Saharan Africa. Lancet Glob Health. 2019; 7(10): e1295–e1296. DOI: 10.1016/S2214-109X(19)30370-5 [DOI] [PubMed] [Google Scholar]
- 19.Deaths from noncommunicable diseases on the rise in Africa | WHO | Regional Office for Africa. Accessed March 4, 2023. https://www.afro.who.int/news/deaths-noncommunicable-diseases-rise-africa.
- 20.HIV/AIDS in Tanzania – NACP-National AIDS Control Programme. Accessed March 2, 2023. https://nacp.go.tz/hiv-aids-in-tanzania/.
- 21.National Bureau of Statistics – The 2017 Tanzania Malaria Indicator Survey Report. Accessed March 2, 2023. https://www.nbs.go.tz/index.php/en/census-surveys/health-statistics/hiv-and-malaria-survey/95-the-2017-tanzania-malaria-indicator-survey-report.
- 22.TB Prevalence in Tanzania | National Tuberculosis & Leprosy Programme. Accessed March 2, 2023. https://ntlp.go.tz/tuberculosis/tb-prevalence-in-tanzania/.
- 23.Tanzania Maternal Mortality Rate 2000–2023 | MacroTrends. Accessed March 2, 2023. https://www.macrotrends.net/countries/TZA/tanzania/maternal-mortality-rate.
- 24.Tanzania NCD Commission Report 2021. Accessed March 2, 2023. https://www.google.com/search?q=tanzania+ncd+commission+report+2021&oq=&aqs=chrome. 0.35i39i362l8.83271680j0j15&sourceid=chrome&ie=UTF-8.
- 25.Shayo FK. Co-occurrence of risk factors for non-communicable diseases among in-school adolescents in Tanzania: An example of a low-income setting of sub-Saharan Africa for adolescence health policy actions. BMC Public Health. 2019; 19(1): 1–8. DOI: 10.1186/s12889-019-7320-1 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 26.Cause of death, by non-communicable diseases (% of total) – Tanzania | Data. Accessed February 19, 2023. https://data.worldbank.org/indicator/SH.DTH.NCOM.ZS?locations=TZ.
- 27.Engelgau M, Rosenhouse S, El-Saharty S, Mahal A. The economic effect of noncommunicable diseases on households and nations: A review of existing evidence. J Health Commun. 2011; 16(SUPPL. 2): 75–81. DOI: 10.1080/10810730.2011.601394 [DOI] [PubMed] [Google Scholar]
- 28.Sunguya BF, Zhu S, Mpembeni R, Huang J. Trends in prevalence and determinants of stunting in Tanzania: An analysis of Tanzania demographic health surveys (1991–2016). Nutr J. 2019; 18(1): 1–13. DOI: 10.1186/s12937-019-0505-8 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 29.Mtongwa RH, Festo C, Elisaria E. A comparative analysis of determinants of low birth weight and stunting among under five children of adolescent and non-adolescent mothers using 2015/16 Tanzania Demographic and Health Survey (TDHS). BMC Nutr. 2021; 7(1): 1–10. DOI: 10.1186/s40795-021-00468-6 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 30.Li X, Zhang M, Pan X, Xu Z, Sun M. “Three hits” hypothesis for developmental origins of health and diseases in view of cardiovascular abnormalities. Birth Defects Res. 2017; 109(10): 744–757. DOI: 10.1002/bdr2.1037 [DOI] [PubMed] [Google Scholar]
- 31.Arima Y, Fukuoka H. Developmental origins of health and disease theory in cardiology. J Cardiol. 2020; 76(1): 14–17. DOI: 10.1016/j.jjcc.2020.02.003 [DOI] [PubMed] [Google Scholar]
- 32.Sunguya BF, Ge Y, Mlunde L, Mpembeni R, Leyna G, Huang J. High burden of anemia among pregnant women in Tanzania: A call to address its determinants. Nutr J. 2021; 20(1): 1–11. DOI: 10.1186/s12937-021-00726-0 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 33.The DHS Program – Tanzania Demographic and Health Survey and Malaria Indicator Survey 2022 – Key Indicators Report (English). Accessed March 2, 2023. https://dhsprogram.com/publications/publication-PR144-Preliminary-Reports-Key-Indicators-Reports.cfm.
- 34.Ministry of Health Tanzania. National Non-Communicable Diseases Research Agenda. 2022. [Google Scholar]
- 35.Tanzania civil society catalyses national NCD programme | NCD Alliance. Accessed February 19, 2023. https://ncdalliance.org/news-events/news/tanzania-civil-society-catalyses-national-ncd-programme.
- 36.Mayige M, Kagaruki G, Ramaiya K, Swai A. Non communicable diseases in Tanzania: A call for urgent action. Tanzan J Health Res. 2011; 13(5 Suppl 1): 1–11. DOI: 10.4314/thrb.v13i5.7 [DOI] [PubMed] [Google Scholar]
- 37.Tanzania NCD Stategic Plan 2016 – 2020 | World Diabetes Foundation. Accessed March 2, 2023. https://www.worlddiabetesfoundation.org/files/tanzania-ncd-stategic-plan-2016-2020.
- 38.Ngalesoni F, Ruhago G, Norheim OF, Robberstad B. Economic cost of primary prevention of cardiovascular diseases in Tanzania. Health Policy Plan. 2015; 30(7): 875–884. DOI: 10.1093/heapol/czu088 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 39.Kitole FA, Lihawa RM, Mkuna E. Comparative analysis on communicable and non-communicable diseases on catastrophic spending and impoverishment in Tanzania. Global Social Welfare. 2022; 1: 1–12. DOI: 10.1007/s40609-022-00241-y [DOI] [PMC free article] [PubMed] [Google Scholar]
- 40.Ministry of Health and Social Welfare. National Noncommunicable Diseases Strategy. Ministry of Health and Social welfare. 2015; (June): 1–16. [Google Scholar]
- 41.Schwartz K, Tutusaus Luque M, Rusca M, Ahlers R. Strategic action plan for prevention and control of non-communicable diseases in Tanzania 2016 – 2020. WIREs Water. 2015; 2(1): 31–36. DOI: 10.1002/wat2.1056 [DOI] [Google Scholar]
