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. Author manuscript; available in PMC: 2023 Nov 17.
Published in final edited form as: Int J Cancer. 2018 Oct 3;143(11):2741–2748. doi: 10.1002/ijc.31735

Table 3.

Risk of Kaposi sarcoma in relation to ambient ultraviolet radiation and diagnosis of skin cancer among solid organ transplant recipients

Factor KS patients Incidence rate, per 100,000 person-years IRR (95% CI)1 p-trend1
Total population
 Ambient UVR tertiles
  T1 (6.0–26.4 mW/m2) 36 8.9 Ref.
  T2 (26.5–43.1 mW/m2) 63 12.5 1.26 (0.84, 1.92)
  T3 (43.2–84 mW/m2) 64 16.0 1.32 (0.87, 2.02) 0.22
Non-Hispanic white transplant recipients
 Ambient UVR tertiles
  T1 (6.0–26.4 mW/m2) 21 6.6 Ref.
  T2 (26.5–43.1 mW/m2) 32 10.0 1.53 (0.89, 2.69)
  T3 (43.2–84 mW/m2) 20 9.3 1.18 (0.64, 2.20) > 0.50
Skin cancer 2 KS cases Controls OR (95% CI) 3 p-value 3
 Squamous cell carcinoma
  No 68 1,435 Ref.
  Yes 5 25 4.83 (1.30, 14.69) 0.02
 Basal cell carcinoma
  No 70 1,439 Ref.
  Yes 3 21 2.95 (0.55, 10.32) 0.20
 Melanoma
  No 72 1,458 Ref.
  Yes 1 2 10.00 (0.17, 192.09) 0.27

Abbreviations: KS, Kaposi sarcoma; IRR, incidence rate ratio; CI, confidence interval; UVR, ultraviolet radiation; T, tertile; OR, odds ratio.

1

Incidence rate ratios based on Poisson regression after adjustment on sex, race, US citizenship, age at transplant (years), calendar year of transplant, and time since transplant (years). p-trend based likelihood ratio tests treating ordinal UVR categories (1–3) as numeric in regression.

2

Diagnoses of squamous and basal cell carcinoma were ascertained by the Scientific Registry of Transplant Recipients, while ascertainment of melanoma was based on cancer registry linkages.

3

Odds ratios based on conditional logistic regression with 20 controls matched to each Kaposi sarcoma case on sex, transplanted organ, age at transplant (±2 years), and calendar year of transplant (±2 years). Restricted to non-Hispanic white transplant recipients. Confidence intervals and p-values based on exact methods.