Table 1.

Allele frequencies of the HLA-A, -B, and -DRB1 genes based on typing results for each HLA gene—considering all patients—and the relative frequency

A locus
HLA-A	N	Genomic frequency	n	Allelic frequency
01	991,473	0.0908	942,988	0.1727
02	2,815,403	0.2578	2,436,090	0.4462
03	1,001,180	0.0917	930,436	0.1704
11	577,712	0.0529	541,262	0.0991
23	567,497	0.0520	534,304	0.0979
24	1,077,242	0.0986	978,044	0.1791
25	135,290	0.0124	128,626	0.0236
26	358,916	0.0329	339,366	0.0622
29	493,343	0.0452	454,497	0.0832
30	589,799	0.0540	552,084	0.1011
31	512,675	0.0469	471,772	0.0864
32	346,690	0.0317	322,012	0.0590
33	337,881	0.0309	316,934	0.0580
34	87,894	0.0080	81,921	0.0150
36	58,873	0.0054	55,898	0.0102
43	770	0.0001	719	0.0001
66	110,563	0.0101	105,005	0.0192
68	677,529	0.0620	615,176	0.1127
69	19,665	0.0018	18,262	0.0033
74	138,028	0.0126	126,996	0.0233
80	21,765	0.0020	20,538	0.0038

B locus
HLA-B	n	Genomic frequency	n	Allelic frequency
07	753,389	0.0690	753,389	0.1380
08	550,405	0.0504	550,405	0.1008
13	169,727	0.0155	169,727	0.0311
14	580,961	0.0532	580,961	0.1064
15	1,010,698	0.0926	1,010,698	0.1851
18	512,680	0.0469	512,680	0.0939
27	240,486	0.0220	240,486	0.0440
35	1,277,037	0.1169	1,277,037	0.2339
37	116,431	0.0107	116,431	0.0213
38	226,718	0.0208	226,718	0.0415
39	370,998	0.0340	370,998	0.0679
40	519,540	0.0476	519,540	0.0952
41	141,988	0.0130	141,988	0.0260
42	161,657	0.0148	161,657	0.0296
44	1,180,839	0.1081	1,180,839	0.2163
45	198,966	0.0182	198,966	0.0364
46	4,285	0.0004	4,285	0.0008
47	23,434	0.0021	23,434	0.0043
48	77,375	0.0071	77,375	0.0142
49	307,257	0.0281	307,257	0.0563
50	265,082	0.0243	265,082	0.0485
51	901,465	0.0826	901,465	0.1651
52	210,625	0.0193	210,625	0.0386
53	271,720	0.0249	271,720	0.0498
54	6,443	0.0006	6,443	0.0012
55	117,657	0.0108	117,657	0.0215
56	38,633	0.0035	38,633	0.0071
57	307,568	0.0282	307,568	0.0563
58	297,219	0.0272	297,219	0.0544
59	1,796	0.0002	1,796	0.0003
67	2,974	0.0003	2,974	0.0005
73	10,559	0.0010	10,559	0.0019
78	9,468	0.0009	9,468	0.0017
81	48,879	0.0045	48,879	0.0090
82	5,213	0.0005	5,213	0.0010
83	16	0.0000	16	0.0000

DRB1 locus
HLA-DRB1	n	Genomic frequency	n	Allelic frequency
01	1,084,612	0.0993	1,028,582	0.1884
03	1,069,711	0.0980	1,015,483	0.1860
04	1,365,429	0.1250	1,276,609	0.2338
07	1,413,774	0.1295	1,319,026	0.2416
08	679,544	0.0622	656,088	0.1202
09	190,245	0.0174	187,774	0.0344
10	219,230	0.0201	216,694	0.0397
11	1,307,580	0.1197	1,223,533	0.2241
12	181,414	0.0166	179,483	0.0329
13	1,472,574	0.1348	1,370,464	0.2510
14	452,605	0.0414	441,819	0.0809
15	1,071,871	0.0982	1,016,277	0.1861
16	411,599	0.0377	402,610	0.0737

30 most frequent HLA-A, -B, and -DRB1 alleles.