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. 2023 Nov 17;9:44. doi: 10.1186/s40729-023-00503-0

Table 1.

PolyP-driven thrombin generation of polyP control

0.15 0.5 1.5 5 15 50 150 500
µg/ml polyP
ETP (nM⋅min) 980.6 ± 201 1108.9 ± 75 1246.8 ± 79 1398.5 ± 76 1398.9 ± 44 1453.9 ± 23 1544.3 ± 55 1522.4 ± 3.1
Peak thrombin (nM) 107 ± 31 143 ± 14 236.6 ± 48 316.4 ± 17 351.7 ± 11 367.6 ± 10 382.9 ± 18 374.6 ± 5.3
Time to peak (min) 21.7 ± 2.3 22.5 ± 0.5 19.5 ± 1.2 13.2 ± 1.5 11 ± 1 9.7 ± 0 8 ± 0.3 7.2 ± 0.2
Lag time (min) 17 ± 2 18.7 ± 0.7 16.7 ± 1.7 11 ± 1.3 9.2 ± 1.2 8 ± 0 6.3 ± 0.3 5.5 ± 0.2

Comparison of thrombin formation in plasma stimulated by increasing concentrations of pure polyp

Values are expressed as mean ± SD, n = 1 in duplicates