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. 2023 Nov 17;13:20147. doi: 10.1038/s41598-023-46193-x

Table 1.

Pharmacophore model evaluation based on Gunner-Henry (GH) scoring method.

S. no Parameters Ph4 model
1 Number of compounds in database (D) 900
2 Number of active in database (A) 48
3 Total Hits (Ht) 50
4 Active Hits (Ha) 40
5 % Yield of actives[(Ha/Ht) × 100] 80
6 % Ratio of actives [(Ha/A) × 100] 83
7 Enrichment factor (E) [(Ha × D)/(Ht × A)] 15
8 False negatives [A − Ha] 8
9 False positives [Ht − Ha] 10
10 GH score 0.79