Figure 1.

Run-time performance, function-level profiling and accuracy comparisons of minimap2 vs. minimap2-fpga. (a) Run-time performance results of original minimap2 vs. minimap2-fpga for ONT $\sim 30\times$ dataset. (b) Run-time performance results of original minimap2 vs. minimap2-fpga for PacBio $\sim 50\times$ dataset. (c) Function-level profiling results of original minimap2. Profiling was done with the Perf profiler⁸ on Intel FPGA-based system for subsets of ONT and PacBio datasets. (d) Function-level profiling results of minimap2-fpga. Profiling was done with the Perf profiler⁸ on Intel FPGA-based system for subsets of ONT and PacBio datasets. (e) Accuracy comparison performed with simulated ONT reads for original minimap2 vs. minimap2-fpga with base-level alignment (raw values in Table 1, plotted data points in Supplementary Table S1). (f) Accuracy comparison performed with simulated ONT reads for original minimap2 vs. minimap2-fpga without base-level alignment (raw values in Table 1, plotted data points in Supplementary Table S1).