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. 2023 Nov 17;14:7473. doi: 10.1038/s41467-023-43038-z

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — a DC populations and their example of canonical markers used in the annotation process. b GO term enrichment of upregulated genes in CD11c-VHHs library injected mice in DCs subpopulations were performed using enricher package, significance was determined by Fisher exact test (−log10) of adjusted p value by benjamini-hochberg (BH) method. c Mean expression of DC activation GO term genes identified in VHHs library injected mice (F Welch test with Holm adjusted p value). d, e Heatmap showing Type 1 interferon, maturation, and regulations genes expression in all samples and cell subpopulations respectively. Source data are provided as a Source Data file.