. 2023 Nov 17;13:20162. doi: 10.1038/s41598-023-46991-3

Table 3.

Summary of the significant FC-trait.

FC-trait	SMN + +	DAN + +	LIMBIC-	VAN + +	DMN +	FPN +	VISUAL-	Striatum-
Main hubs	SMN: Bilateral precentral gyrus, Bilateral postcentral gyrus, Bilateral Somatomotor
Statistics	GROUP rmANOVA F(8,64) = 8.63, p = 5.41 × 10^–4* PD-MCI vs. PD-CN, F(4,41) = 23.09, p = 6.0 × 10^–6* PD-MCI vs. HC, F(4,42) = 29.14, p = 6.0 × 10^–7* PD-CN vs. HC, F(4,40) = 1.03, p = 3.1 × 10^–1, n.s
Associations	Attention and working memory, F(6,119) = 13.244, p = 4.0 × 10^–4* Memory, F(6,119) = 14.129, p = 2.7 × 10^–4* Language, F(6,119) = 8.276, p = 4.8 × 10^–3* MDS-UPDRS-III, F(6,119) = 8.561, p = 4.1 × 10^–3*

FC-trait

SMN + +

DAN + +

LIMBIC-

VAN + +

DMN +

FPN +

VISUAL-

Striatum-

Main hubs

SMN: Bilateral precentral gyrus, Bilateral postcentral gyrus, Bilateral Somatomotor

Statistics

GROUP rmANOVA F(8,64) = 8.63, p = 5.41 × 10^–4*

PD-MCI vs. PD-CN, F(4,41) = 23.09, p = 6.0 × 10^–6*

PD-MCI vs. HC, F(4,42) = 29.14, p = 6.0 × 10^–7*

PD-CN vs. HC, F(4,40) = 1.03, p = 3.1 × 10^–1, n.s

Associations

Attention and working memory, F(6,119) = 13.244, p = 4.0 × 10^–4*

Memory, F(6,119) = 14.129, p = 2.7 × 10^–4*

Language, F(6,119) = 8.276, p = 4.8 × 10^–3*

MDS-UPDRS-III, F(6,119) = 8.561, p = 4.1 × 10^–3*

FC network contributions, main networks, and associations with cognitive and motor functions. FC-Trait F-statistics repeated-measures ANOVA (rmANOVA) model, and the corresponding post-hoc between-group comparisons and associations with cognitive functions are reported.

Network presence for the FC-trait is represented by − or network not present, + or network present with medium strength, and + + or network present with high strength. Asterisks indicate the comparisons that were statistically significant. P-values below 0.05 after FDR correction are considered statistically significant in the rmANOVA model. Between-group post-hoc tests and correlation tests with p-values below 0.01 are considered statistically significant.