Table 1.

List of NS3 drugs^4–7 and the associated DRMs

Drug	Class of DAAs	Residues involved in DRMsa
Telaprevir	NS3-specific	36, 43, 54, 155, 170
Vaniprevir	NS3-specific	36, 155, 168
Boceprevir	NS3-specific	36, 41, 43, 54, 55, 155, 158, 170
Simeprevir	NS3-specific	36, 43, 54, 80, 122, 138, 155, 168, 170
Danoprevir	NS3-specific	41, 43, 138, 155, 168
Glecaprevir	Multi-protein	36, 56, 71, 80, 89, 155, 168, 170
Grazoprevir	Multi-protein	36, 43, 54, 55, 56, 77, 80, 107, 109, 122, 132, 155, 158, 168, 170
Voxilaprevir	Multi-protein	36, 41, 43, 54, 55, 56, 80, 122, 155, 168, 170, 180
Paritaprevir	Multi-protein	36, 43, 56, 80, 122, 155, 168

^aResidues associated SC-DRMs are shown in bold.