Table 1.
Number of isolates sequenced per community carriage survey
| PCV-vaccinated children (2–7 yrs)b | PCV-unvaccinated children (5–10yrs) | Adults (18–40 yrs HIV+ on ART) | |||||
|---|---|---|---|---|---|---|---|
| Survey | Survey dates | Carriage prevalence (%)a | No. of isolates sequenced |
Carriage prevalence (%)a | No. of isolates sequenced |
Carriage prevalence (%)a | No. of isolates sequenced |
| 1 | June 2015 – August 2015 | 241/286 (84.3) | 234 | 174/255 (68.2) | 137 | 78/198 (39.4) | 75 |
| 2 | October 2015–April 2016 | 230/303 (75.9) | 203 | 144/231 (62.3) | 128 | 95/201 (47.3) | 71 |
| 3 | May 2016–October 2016 | 282/361 (78.1) | 247 | 142/242 (58.7) | 114 | 124/279 (44.4) | 0 |
| 4 | November 2016–April 2017 | 351/504 (69.6) | 227 | 75/198 (37.9) | 75 | 132/308 (42.9) | 0 |
| 5 | May 2017–October 2017 | 402/496 (81.1) | 234 | 62/106 (58.5) | 46 | 117/305 (38.4) | 68 |
| 6 | November 2017–June 2018 | 390/610 (63.9) | 220 | 84/173 (48.6) | 62 | 90/277 (32.5) | 53 |
| 7 | June 2018–December 2018 | 390/504 (77.4) | 255 | 113/197 (57.4) | 81 | 78/202 (38.6) | 0 |
| 8 | January 2019–August 2019 | 401/588 (68.2) | 273 | 92/191 (48.2) | 68 | 70/213 (32.9) | 0 |
No. number, yrs years old, PCV pneumococcal conjugate vaccine.
aTotal carriage = all S. pneumoniae isolates (VT, NVT and NT).
Surveys were conducted every 6 months, commencing in June 2015. Columns show the carriage prevalence in each of the 3 cohorts included in this study, and the number of sequenced isolates.
bThere was no recruitment of children aged 2-years during surveys 1–3.