Table 1.
Participant Characteristics of the CITE-seq Cohort
| ID | Age* | Sex† | Gender† | Primary risk factor | Secondary risk factors | Sample day | ARDS | SOFA | P/F Ratio | OI |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 20–30 | M | Man | Trauma | Contusions/Massive Transfusion | 3 | No | 10 | 357 | 2.5 |
| 2 | 20–30 | F | Woman | Trauma | Contusions/Massive Transfusion | 5 | No | 3 | 468 | 3.2 |
| 3 | 40–50 | M | Man | Trauma | Contusions | 2 | No | 7 | 310 | 3.2 |
| 4 | 40–50 | M | Man | Trauma |
Pneumonia/ Contusions |
4 | Yes | 9 | 180 | 5.6 |
| 5 | 50–65 | M | Man | Aspiration Pneumonitis | VT/VF Arrest | 3 | Yes | 13 | 215 | 6.0 |
| 6 | 40–50 | M | Man | Trauma | Pneumonia/Massive Transfusion | 5 | Yes | 7 | 180 | 7.2 |
| 7 | 50–65 | M | Man | NSTI/Sepsis | Volume Overload | 4 | No | 9 | 175 | 8.6 |
| 8 | 50–65 | M | Man | Trauma | Pneumonia | 4 | Yes | 8 | 84 | 13.1 |
|
47 (32–54) |
87% Male |
87% Man |
75% Trauma |
NA |
4 (3–5) |
50% ARDS |
9 (7–10) |
198 (176–345) |
5.8 (3.2–8.3) |
ARDS Acute respiratory distress syndrome, adjudicated at time of bronchoscopy, NSTI Necrotizing soft tissue infection, P/F ratio PaO2/FiO2 ratio; calculated at the time of bronchoscopy (if missing arterial blood gas, SaO2/FiO2 ratio is reported), OI Oxygenation index, Sample Day = interval of days between initiation of invasive mechanical ventilation and bronchoscopy; SOFA Sequential organ failure assessment (calculated at time of bronchoscopy), VT/VF Ventricular tachycardia/ventricular fibrillation
Race and ethnicity were ascertained by participant self-reporting; we do not report individual race/ethnicity to protect participant privacy; 75% of the cohort was white and 25% of the cohort was black
*Age provided as a range to protect participant privacy
†Sex and gender are described based on participant self-reporting