Table 1.

Vein of galen malformation: a scientific and clinical journey targeting the best outcome. Research topics.

VGAM research topics
•Defining genetic background of VGAM
•Embryonic considerations and anatomical features
•Prenatal assessment and prognostic factors
•Pathological features: from brain damage to lung and heart pathological changes secondary to AV shunt and overflow
•Neuroradiological aspects and identification of prognostic factors
•Interventional radiology: treatment challenges
•In utero VGAM treatment
•Intensive care management
•Multidisciplinary long term follow-up and outcomes
•A challenging project: the VGAM International Registry