Table 3.

Performance of Auto BI-RADS and two groups of radiologists for diagnosis of benign and malignant breast lesions in test set.

Parameter	Auto BI-RADS	Experienced Radiologists	Junior Radiologists
AUC	0.87[0.82,0.90]	0.89[0.85,0.92]	0.74 [0.68,0.79] †
Sensitivity (%)	93(116/124)	93(116/124)	72 (91/124)
Specificity (%)	81(136/168)	86(144/168)	74(125/168)
FP (%)	19(32/168)	14(24/168)	26(43/168)
FN (%)	6(8/124)	6(8/124)	25(33/124)
PPV (%)	78(116/148)	82(116/140)	68(91/134)
NPV (%)	94(136/144)	95(144/152)	79(125/158)

—Except where indicated, numbers in parentheses are numbers of lesions and 95% confidence intervals are in brackets.

FP, False Positive; FN, False Positive.

NPV, negative predictive value; PPV, positive predictive value.

† Data are for comparison with Auto BI-RADS (P < 0.001).