Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Aug 22;32(23):3211–3224. doi: 10.1093/hmg/ddad136

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Published by Oxford University Press 2023.

This work is written by US Government employees and is in the public domain in the US.

PMC Copyright notice

Comparing the effect of variants in 3′ UTR regions. A: The proportion of genes with single polyA site usage vs. multiple polyA site usage for 64 case genes with hexamer variants and 60 control genes with control variants. B: The effect of predominant hexamer variants and control variants on alternative polyadenylation (APA). Multiple site genes refers to genes with multiple polyA sites, and single site genes refers to genes with one polyA site. C: The effect of predominant hexamer and control variants on mRNA. D: Gene expression analyses in 65 predominant hexamer variants. The lines from top to bottom denote Bonferroni corrected p-value and p-value = 0.05, respectively.