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. 2023 Nov 18;23:357. doi: 10.1186/s12866-023-03115-1

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — Characteristics of gut microbiota in infantile cholestasis (IC; n = 20) and control (CON; n = 20) groups. A. Distribution of gut microbiota at the phylum level in 40 specimens; B. distribution of gut microbiota at the genus level in 40 samples; C. score plot of differential species showing linear discriminant analysis of differentially abundant genera between the two groups; D. annotated cladogram of differential species showing statistically significant taxa between the two groups; 1E. relative abundance histogram. Solid line represents the mean relative abundance, dashed line represents the median relative abundance; F. distribution of gut microbiota with significant differences in relative abundance between the two groups; G. Heatmap of KEGG pathway enrichment analysis