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. 2005 Mar 15;19(6):733–743. doi: 10.1101/gad.326105

Figure 4.

Figure 4.

Olig3 is essential for the correct specification of class A (dI1-dI3) neurons. The dorsal spinal cord of E11.0 (A-J) and E12.5 (K,L) embryos heterozygous (A,C,E,G,I,K) or homozygous (B,D,F,H,J,L) for the Olig3GILacZ allele were analyzed using antibodies against Lhx2/9 (red) (A,B), Lhx1/5 (red) and Foxd3 (green) (C,D), Tlx3 (red) and Isl1 (green) (E,F), Lbx1 (red) and β-gal (green) (G,H), Lhx1/5 (red) and Pax2 (green) (I,J), and Isl1 (red) and GFP (green) (K,L). The arrow in A points to dI1 neurons. The brackets in C, E, G, and I mark the various indicated neuron types. In D, H, and J, the brackets mark the misspecified dI2/3★ neurons. In K and L, the arrows point to the medial migratory stream of GFP+ neurons, and the arrowheads indicate ectopically located GFP+ neurons in Olig3 mutant embryos. Bars, 100 μm.