Table 2.
Univariable and multivariable ORs to indicate independent risk factors of NASH in NAFLD (n = 88)
| Parameter | Univariate | 95% CI | p | Mutivariate | p | |
|---|---|---|---|---|---|---|
| Odds ratio | Odds ratio | 95% CI | ||||
| AST (U/L) | 1.09 | 1.03–1.15 | < 0.001 | 1.13 | 0.97–1.33 | 0.074 |
| ALT (U/L) | 1.03 | 1.01–1.05 | 0.001 | 1.00 | 0.95–1.06 | 0.939 |
| Triglycerides (mg/dL) | 1.00 | 0.99–1.00 | 0.172 | |||
| ANA | 1.01 | 0.99–1.04 | 0.030 | N. A | ||
| IgG (mg/dL) | 1.00 | 1.00–1.00 | 0.033 | N. A | ||
| Hyaluronic acid (ng/mL) | 1.03 | 1.00–1.06 | 0.001 | 1.05 | 1.00–1.09 | 0.014 |
| Liver stiffness (kPa) | 1.53 | 1.14–2.06 | < 0.001 | 1.55 | 0.94–2.55 | 0.038 |
| NKT cells of CD45 + cells (%) | 2.56 | 1.00–6.54 | 0.027 | N. A | ||
| Th2 of CD4 T cells (%) | 1.76 | 1.13–2.74 | 0.004 | 0.75 | 0.27–2.04 | 0.566 |
| Th17 of CD4 + T cells (%) | 1.93 | 1.29–2.88 | < 0.001 | 2.78 | 1.05–7.36 | 0.013 |
| PD1 + cells of CD8 + T cells (%) | 0.73 | 0.56–0.95 | 0.009 | 0.36 | 0.15–0.87 | 0.002 |
The bold means the parameter significantly indicates risk factors of NASH in univariate or multivariate analysis
Logistic regression was used for univariate and multivariate analysis of the association between significant parameters and indicators of NASH. NA not assessed