Table 4.

Univariable and multivariable ORs to indicate independent risk factors of AIH overlapping NASH in NASH (n = 70)

Parameter	Univariate	95% CI	p	Mutivariate		p
	Odds Ratio			Odds Ratio	95% CI
Male sex (%)	0.19	0.04–0.94	0.031	N. A
ANA	1.01	1.00–1.02	< 0.001	1.00	0.99–1.01	0.688
AMA-M2 (index)	1.12	0.97–1.29	0.107
IgG (mg/dL)	1.00	1.00–1.01	0.003	1.00	0.99–1.01	0.540
IgM (mg/dL)	1.03	1.01–1.04	0.001	1.06	0.95–1.20	0.126
CAP (dB/m)	0.98	0.96–0.99	0.002	0.94	0.84–1.04	0.052
CD4 + T cells of CD45 + cells (%)	1.12	1.03–1.19	0.022	N. A
NK cells of CD45 + cells (%)	0.76	0.58–1.01	0.025	N. A
Th1 of CD4 + T cells (%)	0.86	0.77–0.96	0.006	1.55	0.61–3.93	0.138
Th17 of CD4 + T cells (%)	1.65	1.11–2.443	0.005	0.35	0.06–2.28	0.130
Treg of CD4 + T cells (%)	0.93	0.63–1.38	0.707
PD1 + cells of CD4 + T cells (%)	0.01	0.00–0.23	< 0.001	0.01	0.00–99.1	0.236
PD1 + cells of CD8 + T cells (%)	0.11	0.02–0.67	< 0.001	0.01	0.00–38.9	0.004

Bold values indicate the parameter significantly indicates risk factors of AIH-overlap NASH in univariate or multivariate analysis

Logistic regression was used for univariate and multivariate analysis of the association between significant parameters and indicators of NASH. N. A. not assessed