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. 2023 Nov 6;14:1289198. doi: 10.3389/fimmu.2023.1289198

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Copyright © 2023 Wang, Wang, He, Ji, Pang, Wang, Liu and Ren

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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PRPF19 is significantly expressed in bladder cancer and is linked to high mutation frequency and a poor prognosis. (A, B) PRPF19 mRNA expression level in TCGA-BLCA databases and GSE13507 databases. (C, D) Expression levels of PRPF19 mRNA in low-grade and high-grade samples of TCGA-BLCA databases and GSE13507 databases. (E, F) Correlation between PRPF19 and overall survival in bladder cancer patients. (G, H) Correlation between PRPF19 and disease-free survival in bladder cancer patients. (I, J) Multifactorial COX regression analysis of the prognostic value of PRPF19 in bladder cancer samples. (K) Expression levels of PRPF19 in paired samples of bladder cancer in TCGA database. (L) Top 10 mutated genes in PRPF19 high expression and PRPF19 low expression groups from the TCGA database, shown as a heat map. **p < 0.01 and ***p < 0.001.