Skip to main content
. 2023 Nov 6;15:1267434. doi: 10.3389/fnagi.2023.1267434

Table 3.

Results in domains showing the greatest differences between AD patients and VaD subtypes.

VaD Subtype Domain k n βg [95% ETI] Bayes factor τStudy Newcastle-Ottawa scale
S C E
VaD Digit span backwards S, E, 7 225 0.33 [0.12, 0.52] 9.38 0.05 3 1 1
Delayed recall: Word list S, E 4 235 −0.61 [−0.97, −0.26] 22.71 0.18 3 0 1
Wechsler memory scale verbal recognition 2 85 −1.12 [−1.75, 0.04] 4.72 0.42 3 1 1
CERAD: Word list recognition 4 228 −0.92 [−1.38, −0.43] 19.21 0.27 3 1 1
Other measures of visual memoryS: Delayed recall 5 177 −0.85 [−1.29, −0.32] 13.67 0.18 3 1 1
Immediate visual associative memory 4 354 −1.01 [−1.49, −0.43] 20.02 0.25 3 1 1
sVaD Phonemic fluency S, E, A, G 17 1,460 0.51 [0.22, 0.77] 42.36 0.40 3 1 1
Basic ADLS, E, A, G 3 290 −1.73 [−3.63, 0.01] 4.14 1.92 3 0 1
Graphical sequence test 2 152 0.82 [0.02, 1.47] 3.11 0.36 3 0 1
Delayed recall: Prose 4 670 −0.70 [−1.12, −0.27] 13.11 0.30 3 1 1
Delayed recall: Word list S, E 7 805 −0.64 [−0.88, −0.36] 72.97 0.18 3 1 1
Discriminability in verbal memory 4 489 −0.76 [−1.26, −0.26] 11.50 0.28 3 0 1

Positive effect sizes denote better performance of AD groups and are marked in bold. VaD, Vascular dementia; sVaD, Subcortical vascular dementia. Domain superscripts denote moderators included in the analyses: differences in average dementia severity (S), years of education (E), age (A) and proportion of women (G). k, Number of studies; n, Number of patients; 95% ETI, 95% equal-tailed credible interval. Newcastle-Ottawa-Scale Subscales medians: Selection (S), Comparability (C), Exposure (E). ADL, Activities of daily living. τStudy, Standard deviation of random effects between studies. CERAD, Consortium to Establish a Registry for Alzheimer’s disease Test Battery.