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. 2023 Nov 6;10:1243311. doi: 10.3389/fmed.2023.1243311

Table 2.

Intraoperative medication, surgical strategies, and pathological diagnosis.

OFA group n = 56 OSA group n = 55 p-value
Intraoperative opioid
Intravenous sufentanil (mg) 0 12.80 ± 4.05
epidural hydromorphone (mg) 0 0.39 ± 0.06
Intravenous remifentanil (ug) 0 108.80 ± 78.60
Intraoperative local anesthetics
Intravenous 2% lidocaine (mL) 7.84 ± 2.82 2.51 ± 1.15 <0.001
Intravenous magnesium sulfate (g) 0.38 ± 0.14 0 <0.001
Epidural ropivacaine (mL) 18.16 ± 2.65 14.38 ± 1.81 <0.001
Intraoperative rescue medication
Ephedrine (mg) 4.02 ± 5.21 7.98 ± 7.67 0.005
Phenylephrine (mg) 0.25 ± 0.28 0.21 ± 0.30 0.444
Norepinephrine bitartrate (mg) 0.06 ± 0.12 0.03 ± 0.05 0.174
Surgical choices, n (%) 0.337
Lobectomy 6 (10.7%) 13 (23.6%)
Segmentectomy 12 (21.4%) 11 (20.0%)
Wedge resection 26 (46.4%) 22 (40.0%)
Combined 12 (21.4%) 9 (16.4%)
Pathological diagnosis, (n) 0.615
Adenocarcinoma 51 50
Benign or atypical lesions 4 2
Lymphoma 1 1
Hamartoma 0 1
Neuroendocrine tumor 0 1

Continuous variables are expressed as mean ± SD. Discrete variables are expressed as count (percentage).