Table 3.

Histological score of wound healing process (mean ± SD) by hematoxylin and eosin (H&E) staining in a control (CG) and an ozonated water (O3W) group at 7th, 14th, 21st, and 28th days post-wounding.

Day post-wounding	Groups	Formation of epithelium	Formation of new vessels	Formation of granulation tissue	Proliferation of fibroblasts	Infiltration of inflammatory cells
7th	CG	1 ± 0.9	0.43 ± 0.61	1.62 ± 0.15	0.91 ± 0.57	1.87 ± 0.71
	O3W	2.03 ± 0.1*	2.03 ± 0.80*	2.36 ± 0.53*	2.08 ± 0.41*	1.37 ± 0.31*
14th	CG	1.87 ± 0.47	0.90 ± 0.11	1.89 ± 0.33	1.91 ± 0.07	1.49 ± 0.60
	O3W	2.71 ± 0.07*	2.58 ± 0.42*	2.59 ± 0.39*	2.53 ± 0.25*	0.97 ± 0.32*
21st	CG	2.04 ± 0.08	1.69 ± 0.02	2.06 ± 0.60	1.80 ± 0.19	1.09 ± 0.21
	O3W	3.00 ± 0.00*	2.83 ± 0.17*	2.9 ± 0.08*	2.97 ± 0.01*	0.67 ± 0.11*
28th	CG	2.52 ± 0.47	2.02 ± 0.52	2.29 ± 0.41	2.83 ± 0.07	0.97 ± 0.56
	O3W	3.00 ± 0.00*	3.00 ± 0.00*	3.00 ± 0.00*	3.00 ± 0.00*	0.47 ± 0.21*

^(*)Means different between the same raw (between groups) are statistically significant at (p ≤ 0.05).