Fig. 1.

Dioscin improves the behavior of mice induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). (A) The group assignments and time line of the experimental process. (B) Motor behavior of mice after dioscin treatment on MPTP-induced Parkinson's disease (PD) model, including pole test and traction test. (C) CatWalk print and mean intensity of the corresponding print of mice after dioscin treatment on MPTP-induced PD model. The upper panel (green prints in black background) shows the digitized prints, and the lower panel shows walking pattern and individual paws (RF: right front; RH: right hind; LF: left front; and LH: left hind). (D) The mice gait behavior indicators change after dioscin treatment on MPTP-induced PD model, including average speed, stands, step cycle, stride length, swing speeds and the base of support. All data are given as mean ± standard deviation (SD) (n = 8). ^∗P < 0.05 and ^∗∗P < 0.01 compared with MPTP group.