Skip to main content
. Author manuscript; available in PMC: 2025 Feb 1.
Published in final edited form as: Neurol Clin. 2023 Aug 7;42(1):77–114. doi: 10.1016/j.ncl.2023.06.009

Figure 6. MRI examples of brain lesions in patients with MOGAD.

Figure 6.

Top row shows MRI findings during the acute phase, while follow-up up imaging is displayed in the bottom row. Images are in axial view.

Poorly defined (i.e., fluffy) T2-lesions in the entire medulla and cerebellum (A, arrows), completely resolving at follow-up imaging (E). Bilateral fluffy T2-lesions in the middle cerebellar peduncles (B, arrows) with reduction in size but persistence at follow-up (F, arrows) with accompanying fourth ventricle ex vacuo enlargement. Bilateral fluffy T2-lesions of the thalami (C, arrows) in a patient with prominent leptomeningeal enhancement (zoom-in picture, post-contrast T1-weighted sequence) undergoing complete resolution at follow-up (G). Patient with cerebral cortical encephalitis showing an extensive cortical T2-lesion (D, arrow) with focal enhancement (zoom-in picture, post-contrast T1-weighted sequence), completely resolved at follow-up (H).

Abbreviations: FLAIR=fluid-attenuated inversion recovery; Gd=post-contrast T1-weighted images; MOGAD=myelin oligodendrocyte glycoprotein antibody-associated disease.