Table 1. Effects of taxifolin on aspirin-induced ulcers in rats.
| Group | Number of animals | Total ulcer area (mm2) | Anti-ulcer effect (%) |
|---|---|---|---|
| HC | 6 | 0 | – |
| AS | 6 | 83.33 ± 1.45* | 0 |
| T+AS | 6 | 1.33 ± 0.42** | 98.4 |
| F+AS | 6 | 5 ± 0.57** | 93.9 |
HC, healthy control; AS, 100 mg/kg aspirin; T+AS, 50 mg/kg taxifolin + 100 mg/kg aspirin; F+AS: 20 mg/kg famotidine + 100 mg/kg aspirin. The results are presented as the mean ± SEM. For comparisons of groups, one-way ANOVA was used. After ANOVA, according to the homogeneity of variances, the post hoc LSD (least significant difference) test was used. *P<0.001 compared with the HC group. **P<0.001 compared with the AS group.