Table 2. Glutathione (GSH), malondialdehyde (MDA), total oxidant capacity (TOS), and total antioxidant status (TAS) measurement results for aspirin-induced ulcers in rats.
| Group | tGSH (nmol/g protein) |
MDA (µmol/g protein) |
TOS (nmol H2O2/mg protein) |
TAS (µmol Trolox equiv./mg protein) |
|---|---|---|---|---|
| HC | 6.25 ± 0.06 | 3.20 ± 0.04 | 2.25 ± 0.05 | 5.18 ± 0.05 |
| AS | 3.48 ± 0.11* | 5.47 ± 0.09* | 4.09 ± 0.16* | 2.70 ± 0.23* |
| T+AS | 5.60 ± 0.09** | 3.37 ± 0.06** | 2.47 ± 0.16** | 4.61 ± 0.13** |
| F+AS | 5.77 ± 0.04** | 3.27 ± 0.03** | 2.36 ± 0.08** | 4.86 ± 0.08** |
HC, healthy control; AS, 100 mg/kg aspirin; T+AS, 50 mg/kg taxifolin + 100 mg/kg aspirin; F+AS: 20 mg/kg famotidine + 100 mg/kg aspirin.The results are presented as mean ± SEM. For comparisons of groups, one-way ANOVA was used. After ANOVA, according to the homogeneity of variances, the post hoc LSD (least significant difference) test was used. * P<0.001 compared with the HC group. ** P<0.001 compared with the AS group.