Table 3.
Clinical responder and UPCR reduction from baseline by 30% and 50%
| Clinical responder (UPCR <0.5 mg/mg), n (%) | ||
|---|---|---|
| Analysis visit | UPCR, mg/mg | C3G (n = 8) |
| Baseline | ≥0.5 | 8 (100) |
| Week 48 | <0.5 | 2 (25.0) |
| ≥0.5 | 5 (62.5) | |
| UPCR reduction from baseline by 30% and 50%, n (%) | ||
|---|---|---|
| Analysis visit | UPCR reduction from baseline | C3G (n = 8) |
| Week 48 | <30% | 1 (12.5) |
| ≥30% | 6 (75.0) | |
| <50% | 4 (50.0) | |
| ≥50% | 3 (37.5) | |
C3G, C3 glomerulopathy; UPCR, urine protein-to-creatinine ratio.
Sample size n = 8 at baseline and n = 7 at week 48 due to 1 participant who stopped study drug at week 24.