Table 1.
Patient baseline demographic characteristics
| Demographics |
Total cohort |
Development set n = 811 |
Critically ill n = 112 | Validation set n = 543 |
Critically ill n = 87 |
|---|---|---|---|---|---|
| Subgroup: state of kidney function | n = 1354 | Stable n = 699 | Stable n = 456 | ||
| Age (yrs) | 60 [48–68] | 59 [47–66] | 69 [62–74] | 57 [47–66] | 65 [59–74] |
| Gender, male n (%) | 794 (59) | 373 (53) | 95 (85) | 251 (55) | 75 (86) |
| Race, n (%) | |||||
| African American | 25 (2) | 18 (3) | 1 (1) | 9 (2) | |
| American Indian | 11 (1) | 6 (1) | 5 (1) | ||
| Asian American | 30 (2) | 16 (2) | 14 (3) | ||
| White | 1235 (91) | 630 (90) | 111 (99) | 407 (90) | 87 (100) |
| Creatinine (μmol/l) | 115 [88–142] | 115 [97–150] | 83 [70–99] | 115 [88–150] | 77 [66–93] |
| Proenkephalin (pmol/l) | 76 [55–109] | 80 [58–113] | 53 [38–68] | 85 [61–114] | 53 [40–62] |
| Measured GFR (ml/min/1.73 m2) | 61 [44–81] | 57 [42–75] | 94 [69–111] | 55 [41–74] | 95 [74–113] |
GFR, glomerular filtration rate.
Data are presented as frequency (percentage) or median [interquartile range].
GFR was measured using gold standard iothalamate or iohexol clearance.
Conversion factors for units: serum creatinine in mg/dl to μmol/l, ×88.42.