Table 2.
Effects of KRGF on body weight, food intake, food efficacy ratio and liver weight in NAFLD-induced rats (mean ± SD, n = 8).
NC | HF | LD | HD | PC | |
---|---|---|---|---|---|
Initial BW (g) | 346.75 ± 15.83 | 353.63 ± 23.48 | 352.63 ± 31.40 | 361.75 ± 28.06 | 366.25 ± 17.30 |
Final BW (g) | 407.38 ± 27.32 | 442.50 ± 23.32# | 436.88 ± 36.20 | 445.25 ± 40.57 | 433.38 ± 19.05 |
BW gains (g) | 60.63 ± 27.26 | 88.88 ± 8.32## | 84.25 ± 9.43 | 83.50 ± 17.67 | 67.13 ± 16.13* |
Food intake (g) | 588.71 ± 13.96 | 688.97 ± 5.76### | 669.52 ± 22.32* | 702.76 ± 7.47 | 669.54 ± 13.16* |
FER (%) | 10.25 ± 4.60 | 12.90 ± 1.19 | 12.57 ± 1.15 | 11.89 ± 2.55 | 10.00 ± 2.29* |
Liver weight (g) | 11.06 ± 0.87 | 18.25 ± 1.33### | 18.45 ± 1.18 | 18.65 ± 1.83 | 18.95 ± 1.48 |
Liver weight/BW (%) | 2.70 ± 0.16 | 4.06 ± 0.19### | 4.10 ± 0.34 | 4.13 ± 0.22 | 4.38 ± 0.35 |
BW, body weight; FER, food efficacy ratio = (body weight gain/food intake) × 100 %; NC, normal control group; HF, HFD-induced control group; LD, HFD + low-dose KRGF (325 mg/kg/day); HD, HFD + high-dose KRGF (650 mg/kg/day); PC, HFD + fenofibrate (25 mg/kg/day). Values are expressed as mean ± SD (n = 8 for each group). #p < 0.05, ##p < 0.01, ###p < 0.001 vs. NC; *p < 0.05 vs. HF.