Table 3.
Subgroup analysis and interaction test.
| Middle-aged | Elderly | P for interaction | |
|---|---|---|---|
| For BVF1 | 0.976 (0.944, 1.009) 0.1543 | 0.996 (0.957, 1.036) 0.8338 | 0.3758 |
| For TRN1 | 0.961 (0.927, 0.996) 0.0313 | 0.980 (0.941, 1.021) 0.3365 | 0.3928 |
| For TRTH1 | 0.962 (0.929, 0.996) 0.0277 | 0.947 (0.906, 0.990) 0.0165 | 0.5253 |
| For TRSP1 | 0.962 (0.929, 0.997) 0.0343 | 0.945 (0.899, 0.994) 0.0281 | 0.4851 |
|
Male |
Female |
||
| For BVF1 | 0.996 (0.960, 1.032) 0.8062 | 0.971 (0.936, 1.007) 0.1183 | 0.2692 |
| For TRN1 | 0.963 (0.925, 1.003) 0.0665 | 0.969 (0.935, 1.004) 0.0832 | 0.7853 |
| For TRTH1 | 0.957 (0.918, 0.997) 0.0334 | 0.956 (0.920, 0.994) 0.0226 | 0.9922 |
| For TRSP1 | 0.969 (0.928, 1.013) 0.1651 | 0.952 (0.914, 0.991) 0.0176 | 0.4716 |
|
KL grade: 0,1 |
KL grade: 2,3,4 |
||
| For BVF1 | 0.969 (0.920, 1.020) 0.2280 | 0.986 (0.958, 1.016) 0.3555 | 0.4862 |
| For TRN1 | 0.960 (0.913, 1.009) 0.1108 | 0.969 (0.939, 1.001) 0.0540 | 0.7052 |
| For TRTH1 | 0.962 (0.915, 1.012) 0.1311 | 0.955 (0.923, 0.988) 0.0084 | 0.7836 |
| For TRSP1 | 0.954 (0.903, 1.008) 0.0934 | 0.960 (0.927, 0.995) 0.0255 | 0.8129 |
|
Low calcium intake |
High calcium intake |
||
| For BVF1 | 1.011 (0.968, 1.057) 0.6222 | 0.971 (0.939, 1.005) 0.0917 | 0.1119 |
| For TRN1 | 1.003 (0.959, 1.049) 0.8980 | 0.949 (0.913, 0.986) 0.0076 | 0.0333 |
| For TRTH1 | 0.978 (0.933, 1.024) 0.3449 | 0.946 (0.911, 0.983) 0.0048 | 0.2207 |
| For TRSP1 | 1.006 (0.959, 1.056) 0.7991 | 0.935 (0.894, 0.977) 0.0030 | 0.01 |
|
Low magnesium intake |
High magnesium intake |
||
| For BVF1 | 1.004 (0.966, 1.044) 0.8232 | 0.969 (0.932, 1.007) 0.1062 | 0.1713 |
| For TRN1 | 0.962 (0.918, 1.009) 0.1126 | 0.971 (0.937, 1.007) 0.1158 | 0.7517 |
| For TRTH1 | 0.979 (0.939, 1.020) 0.3070 | 0.942 (0.901, 0.984) 0.0076 | 0.186 |
| For TRSP1 | 0.968 (0.920, 1.019) 0.2124 | 0.957 (0.918, 0.997) 0.0343 | 0.7087 |
Adjusted for age, sex, race, BMI, Kellgren-Lawrence (KL) grade, and PASE score, alcohol use, smoking status, history of bone fracture after the age of 45, history of hip fracture, history of vertebral/spine fracture, history of oral corticosteroid medication use, history of bisphosphonate intake, intact parathyroid hormone level, serum 25-vitamin D level and calcium and magnesium intake.