Table 3.
Proportion of AKI risk factors
| AKI risk factor, n (%) | Entire cohort (N = 314) | DI-AKI (n = 271) | Not DI-AKI (n = 43) | P-value |
|---|---|---|---|---|
| Hyperglycemia | 144 (45.86) | 131 (48.34) | 13 (30.23) | 0.03 |
| Severe infection or sepsis | 56 (17.83) | 50 (18.45) | 6 (13.95) | 0.67 |
| Extracellular fluid loss | 41 (13.06) | 38 (14.02) | 3 (6.98) | 0.33 |
| Red blood cells transfusion | 39 (12.42) | 30 (11.07) | 9 (20.93) | 0.08 |
| Intravascular fluid loss | 37 (11.78) | 34 (12.55) | 3 (6.98) | 0.44 |
| Other procedures | 31 (9.9) | 29 (10.7) | 2 (4.7) | 0.28 |
| Liver disease | 30 (9.55) | 24 (8.86) | 6 (13.95) | 0.27 |
| Anesthetic agent | 28 (8.92) | 22 (8.12) | 6 (13.95) | 0.24 |
| Cardiac failure | 27 (8.6) | 25 (9.23) | 2 (4.65) | 0.56 |
| Increased vascular capacity | 14 (4.46) | 9 (3.32) | 5 (11.63) | 0.03 |
| Cardiac surgery | 7 (2.23) | 3 (1.11) | 4 (9.3) | <0.01 |
| Vascular surgery | 4 (1.27) | 3 (1.11) | 1 (2.33) | 0.45 |
| Hepatorenal syndrome | 3 (0.96) | 3 (1.11) | 0 (0) | 1 |
| Hemorrhage | 2 (0.64) | 2 (0.74) | 0 (0) | 1 |
AKI, acute kidney injury; DI-AKI, drug-induced acute kidney injury; RBC, red blood cell.
AKI risk factors were considered to be present if they were recorded in the 72 hours preceding AKI onset.
Increased vascular capacity was defined as clinical events leading to reduced blood perfusion (e.g., mean arterial pressure <65 mm Hg, sepsis). Hyperglycemia was defined as blood sugar >110 mg/dl or the patient is on insulin.