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. 2023 Aug 16;8(6):e10586. doi: 10.1002/btm2.10586

TABLE 2.

Predictive ability of defined IC50 cutoff value in PDTO drug test for adjuvant chemotherapy response prediction.

N = 86 Response in the clinic
Response N = 59 Nonresponse N = 27
Drug response in PDTO Sensitive, N = 54 50 4 PPV = 92.59% (50/54)
Resistant, N = 32 9 23 NPV = 71.88% (23/32)
Sens = 84.75% (50/59) Spec = 85.19% (23/27) Accuracy = 84.88% (73/86)

Abbreviations: NPV, negative predictive value; PDTO, patient‐derived tumor organoid; PPV, positive predictive value; Sens, sensitivity; Spec, specificity.