TABLE 1.
Information on the breed, clinical phenotype (spinocerebellar‐like ataxia and myokymia/neuromyotonia) and genotype (KCNJ10 and CAPN1) of the 33 investigated dogs.
| Breed | SCA | M/NM | KCNJ10 | CAPN1 | Number |
|---|---|---|---|---|---|
| JRT | + | + | G/G | G/G | 19 a |
| Dachshund | + | + | G/G | G/G | 1 b |
| Mixed breed | + | + | G/G | G/G | 1 |
| JRT | + | − | G/G | G/G | 5 |
| JRT cross | + | − | G/G | G/G | 1 |
| PRT | + | − | C/C | A/A | 1 |
| JRT | + | − | C/C | G/G | 1 |
| JRT | − | + | C/C | G/G | 3 c |
| YT | − | + | C/C | G/G | 1 |
Note: Variant alleles are in bold.
Abbreviations: CAPN1, XM_038425033.1:c.344G>A (p.(Cys115Tyr)) CAPN1 genotype; JRT, Jack Russell terrier; KCNJ10, XM_038448705.1:c.627C>G (p.(Ile209Met)) KCNJ10 genotype; M/NM, myokymia and/or neuromyotonia; PRT, Parson Russell terrier; SCA, spinocerebellar ataxia; YT, Yorkshire terrier.
a
Eight dogs were clinically described in reference 9.
b
This dog was described in reference 26.
c
One dog was described in reference 9.