Table 4.
Trajectory of multimorbidity in incident rheumatoid arthritis (RA) compared to non-RA patients
| A. Primary analysis (n=44 conditions) |
B. Secondary analysisa (n=36 conditions) |
C. 2 years pre-index date (n=44 conditions) |
||||
|---|---|---|---|---|---|---|
| β (95% CI) | P | β (95% CI) | P | β (95% CI) | P | |
| RA vs. non-RA | 1.13 (1.10, 1.17) | <0.001 | 0.62 (0.59, 0.64) | <0.001 | 0.29 (0.27, 0.31) | <0.001 |
| Year of follow-up | 0.24 (0.23, 0.24) | <0.001 | 0.18 (0.18, 0.19) | <0.001 | 0.48 (0.47, 0.49) | <0.001 |
| RA x time (years) | 0.21 (0.20, 0.21) | <0.001 | 0.12 (0.11, 0.13) | <0.001 | 0.33 (0.32, 0.35) | <0.001 |
| Age (per year) | 0.06 (0.06, 0.06) | <0.001 | 0.05 (0.05, 0.05) | <0.001 | 0.04 (0.04, 0.04) | <0.001 |
| Female sex | 0.28 (0.24, 0.32) | <0.001 | 0.15 (0.12, 0.18) | <0.001 | 0.16 (0.12, 0.20) | <0.001 |
a
Excluded conditions known to be related to RA or could be misclassified as RA
A & B. N=61,528 patients and 173,469 observations
C. N=33,202 patients and 153,121 observations