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Plasma pharmacokinetics of agmatine after intravenous and oral administration in Sprague-Dawley rat. (A) Plasma concentration-time profiles after a single i.v. dose via jugular catheter of 3 or 30 mg/kg agmatine sulfate in Sprague-Dawley rat (n = 10 and 9, respectively). (B) Plasma concentration-time profiles after a single oral dose via oral gavage of 100 or 300 mg/kg agmatine sulfate in Sprague-Dawley rat (n = 6 and 8, respectively). Data are presented as mean ± S.E.M.
