Table 1.
Baseline clinical characteristics and intraoperative variables of Group L and Group H
| Clinical variable | Group L, n = 44 | Group H, n = 44 | P value |
|---|---|---|---|
| Preoperative index | |||
| Age (y) | 66.0(62.3–71.8) | 68.0(65.3–70.0) | 0.313 |
| BMI (kg/m2) | 24.1(21.3–25.1) | 24.2(23.0–28.0) | 0.502 |
| Gender (female) | 18(40.9) | 23(52.3) | 0.285 |
| MMSE0 | 28.0(26.0–29.0) | 27.5(26.0–28.0) | 0.259 |
| ASA | 0.560 | ||
| III n (%) | 6(13.6) | 8(18.2) | |
| IV n (%) | 38(86.4) | 36(81.8) | |
| Type of surgery | > 0.999 | ||
| Valve surgery n (%) | 39(88.6) | 39(88.6) | |
| Aortic root surgery n (%) | 5(11.4) | 5(11.4) | |
| EF (%) | 64.2 ± 7.9 | 63.8 ± 6.9 | 0.797 |
| Educational level < 5 years n(%) | 20(45.5) | 23(52.3) | 0.522 |
| CAS ≥ 50% n (%) | 2(4.5) | 10(22.7) | 0.013 |
| Smoking n (%) | 0(0) | 1(2.3) | > 0.999# |
| Hypertension n (%) | 25(56.8) | 13(29.5) | 0.010 |
| Diabetes n (%) | 6(13.6) | 6(13.6) | > 0.999 |
| Haemoglobin(g/L) | 126.4 ± 16.3 | 120.1 ± 16.7 | 0.076 |
| Inoperative index | |||
| CPB time (min) | 119.5(100.3–155.0) | 114.5(101.0-159.0) | 0.897 |
| Benzenediazepines use n (%) | 38(86.4) | 38(86.4) | > 0.999 |
| Penehyclidine hydrochloride use n (%) | 35(79.5) | 39(88.6) | 0.244 |
| Length of surgery (min) | 280.0(250.0-351.3) | 290.0(255.0-347.5) | 0.652 |
| Anaesthesia time (min) | 330.0(296.3-393.8) | 345.0(320.0-400.0) | 0.316 |
| Sufentanil (ug) | 350.0(311.8–395.0) | 350.0(317.3-406.8) | 0.698 |
| Propofol (mg) | 1100.0(989.5-1283.5) | 1120.0(1000.0-1200.0) | 0.776 |
| DEX infusion time (h) | 18.5(14.0–22.0) | 20.0(14.0-26.8) | 0.410 |
Data are shown as the mean ± standard deviation, number (percent), or median (interquartile range) as appropriate. #Fisher's exact test
BMI Body mass index, MMSE0 baseline Mini-Mental State Evaluation, ASA American Statistical Association, EF Ejection fraction, CAS Carotid artery stenosis, CPB Cardiopulmonary bypass, DEX Dexmedetomidine