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. 2023 Nov 17;24(9):788–796. doi: 10.1089/sur.2023.161

FIG. 2.

FIG. 2.

Hepatic and renal mitochondrial content and function after cecal ligation and puncture (CLP) or sham surgery in wild-type (WT) and Sirt3 knockout (S3KO) mice. Respiratory function is determined by rate of oxygen consumption (nmol O2/mg/min). Rate of oxygen consumption was measured for fatty acid oxidation (FAO) and mitochondrial CI (complex I), CII (complex II), and CIV (complex IV). A: Oxygen consumption in hepatic tissue at 36 hours after CLP. B: Oxygen consumption in hepatic tissue at five days after CLP. C: Oxygen consumption in renal tissue at 36 hours after CLP. D: Oxygen consumption in renal tissue at five days after CLP. Mitochondrial content is measured by citrate synthase activity at 36 hours and five days in liver (E) and kidney (F). *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001.