Table 1.
Enrollment characteristics of older breast cancer survivors and frequency-matched non-cancer controls1
| Survivors (n = 89) | Non-cancer controls (n = 101) | ||
|---|---|---|---|
|
|
|||
| Baseline characteristics | Mean (SD) or percent (n) | p-value | |
|
| |||
| Chronological age (years) | 70.73 (4.54) | 70.38 (5.06) | .62 |
| Race2 | |||
| American Indian/Alaska Native | 0.0 (0) | 1.0 (1) | .54 |
| Asian | 6.7 (6) | 2.0 (2) | |
| Black or African American | 7.9 (7) | 8.9 (9) | |
| Multiracial/Other | 3.4 (3) | 2.0 (2) | |
| White, Hispanic | 4.5 (4) | 5.9 (6) | |
| White, Non-Hispanic | 77.5 (69) | 80.2 (81) | |
| Education (years) | 15.66 (1.97) | 15.52 (2.48) | .67 |
| Marital status | |||
| Married or living as married | 63.6 (56) | 56.0 (56) | .28 |
| Other | 36.4 (32) | 44.0 (44) | |
| Missing | 1.1 (1) | 1.0 (1) | |
| Cognitive reserve, WRAT-4 Word Reading score | 112.03 (15.08) | 112.82 (17.76) | .74 |
| Number of comorbidities | |||
| ≤ 2 (median) | 50.6 (44) | 56.6 (56) | .41 |
| > 2 | 49.4 (43) | 43.4 (43) | |
| Missing | 2.2 (2) | 2.0 (2) | |
| AJCC stage | |||
| 0 | 15.7 (14) | ||
| I | 61.8 (55) | ||
| II | 16.9 (15) | ||
| III | 5.6 (5) | ||
| Molecular subtype | |||
| ER+ and HER2− | 75.6 (62) | ||
| HER2+ | 17.1 (14) | ||
| Triple negative | 7.3 (6) | ||
| Missing | 7.9 (7) | ||
| Surgery | |||
| Lumpectomy with radiotherapy | 43.8 (39) | ||
| Lumpectomy without radiotherapy | 12.4 (11) | ||
| Mastectomy | 43.8 (39) | ||
| Hormonal therapy regimen | |||
| Aromatase inhibitor | 89.7 (61) | ||
| Tamoxifen | 10.3 (7) | ||
| None | 23.6 (21) | ||
| Chemotherapy regimen | |||
| AC (no T) | 6.9 (2) | ||
| AC+T | 55.2 (16) | ||
| CMF | 3.4 (1) | ||
| T only | 34.5 (10) | ||
| None | 67.4 (60) | ||
1
Enrollment was pre-systemic therapy for survivors or study start for controls.
2
Racial/ethnic groups were collapsed to Black vs. non-Hispanic white for analyses.
AC = Adjuvant chemotherapy (doxorubicin and cyclophosphamide); T = Taxotere; CMF = cyclophosphamide, methotrexate, and 5-fluorouracil; p-values were derived from t-tests or chi-square tests; p-values <.05 appear in bold font.