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. Author manuscript; available in PMC: 2024 Nov 1.
Published in final edited form as: Comput Toxicol. 2023 Nov;28:1–17. doi: 10.1016/j.comtox.2023.100287

Figure 4. Qualitative concordance between SUB and CHR organ-level effects.

Figure 4.

In A, the odds ratio of a positive finding in the CHR study for an organ given a positive finding in the SUB study (subset by species groupings, as indicated by asterisk for all species, filled triangle for dog, filled diamond for mouse, upside down empty triangle for rat, and empty diamond for rodent). Color indicates organ. The dot represents the odds ratio, and the line segment demonstrates the distance from the lower 95% CI bound to the upper 95% CI bound for the odds ratio. Sample sizes for rat, mouse, dog, rodent, all were 313, 179, 152, 159, and 60 chemicals (with SUB and CHR studies available).