Table 1.

Model parameters and their descriptions

parameter	corresponding event	description
${\text{K}}_1$	1,2	rates of HOPS recruitment and turnover
${\text{K}}_3$	3	chaperoning rate
${\text{K}}_4$	4	rate of HOPS:trans-SNARE super-complex dissociation
$\mathrm{\alpha }\left(={\text{K}}_5/{\text{K}}_4\right)$	5	HOPS & trans-SNARE reassociation rate expressed relative to HOPS:trans-SNARE dissociation rate
${\text{K}}_6$	6	rate of Sec17 recruitment
${\text{K}}_7$	7	rate of Sec17 turnover
$\mathrm{\beta }\left(={\text{K}}_8/{\text{K}}_9\right)$	8	rate for Sec17 displacement of HOPS expressed relative to rate for Sec17 association with trans-SNARE complexes
${\text{K}}_9$	9	rate of Sec17 association with trans-SNARE complexes