Figure 5: Thalamus representations of disuse-driven FC changes, pulses and hand movement task fMRI activations.

(A) Map of disuse-driven increases in FC with left SM1_ue region of interest (top 30^th percentile t statistics). (B) Map of disuse pulses (top 30^th percentile t statistics). (C) Map of precasting task fMRI contrast : right hand movement vs baseline (top 30^th percentile t statistics). For all three maps, color scales are represented at the bottom of the map with maximum value at 99.5^th percentile. For all three maps, color scales are represented at the bottom of the map with maximum value at 99.5^th percentile. Nucleus borders from the THOMAS individual-based segmentation overlapping with the effects are visible in white. Four nuclei are displayed : CM: centro-median , VPL: ventro-posterior lateral , VIM(VLPv): ventral intermediate (ventro-lateral posterior ventral), MD-Pf: medio-dorsal. Average t-statistics values for all thalamic nuclei are represented in bar plots (see figure S4) (D) Correlation between left thalamic t statistic maps for disuse-driven FC increases, pulse and activation during hand movement (right hand vs baseline). Correlations between unthresholded t statistics maps were tested against individual-specific null distribution effects for each participant (top to bottom : Nico, Ashley, Omar). Reported significant p < 0.05 corrected for FDR (black *).