Figure 1. Multistate transitions over time.

A. We depict the potential one-step transitions in our multistate framework. Per year, an individual can progress from health to single risk factor states, CAD or death. Similarly, an individual can progress from single risk factor states, to double risk factor states, to CAD or death; from double risk factor states, to triple risk factor, CAD or death. B. We display the proportional occupancy excluding censored individuals at each state. M

CAD: coronary artery disease, Ht: hypertension, HyperLip: hyperlipidemia, Dm: Type 2 diabetes mellitus.