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[Preprint]. 2023 Nov 7:rs.3.rs-2802998. [Version 1] doi: 10.21203/rs.3.rs-2802998/v1

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Extended Data Figure 5: — a, Transcriptional start site (TSS) enrichment scores for all samples. b, Pearson correlation and hierarchical clustering of ATAC-sequencing data. c-f, Bulk ATAC-seq analyses of day 15 tNGFR-purified, CD8+ CD19.28ζ CAR T cells overexpressing tNGFR (black), TCF1 (red) or FOXO1 (blue) (n = 3 independent donors). c, Principal component analysis (PCA). d,e, Rank ordered plot of differentially accessible transcription factor binding motifs in FOXO1_OE cells (d) and TCF1_OE cells (e) versus tNGFR controls. Transcription factor families are annotated by color. f, Heatmap and hierarchical clustering of mean differential motif accessibility. Scale shows normalized z-scores for each motif.