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[Preprint]. 2023 Nov 6:rs.3.rs-3429258. [Version 1] doi: 10.21203/rs.3.rs-3429258/v1

Figure 2. Microparticle release of NRG1.

Figure 2.

A, (a) 28-day NRG1 release profile; (b) Characterization of the PLGA microparticle size and polydispersity index. B, Representative confocal images of DRG explants. DRGs were immunostained for axon (β-tubulin, green) and cell nuclei (DAPI, blue). Neurites were highlighted by white arrows while cell bodies were highlighted in yellow dashed circles. Scale bar: 100 μm. C, Quantification of the mean and maximum neurite length of DRG explants cocultured with empty, NRG1, PTN, and PTN-NRG1 microspheres for one week. **, p<0.01.