Table 2.

Clinical Examples for MADE Score determination

6 yo new diagnosis DMD, muscle cramps, toe walking, HR 90, echo normal, negative ROS
CARDIAC		PULMONARY		MYOPATHY		NUTRITION		TOTAL MADE
none	0	none	0	Toe walking	1	none	0
Domain Points	0		0		1		0	1
12 yo HR 110, echo normal, CMRI delayed enhancement, snores w OSA no therapy, ambulates in house, no stairs, limited arm raise, fatigue after activity, negative ROS
CARDIAC		PULMONARY		MYOPATHY		NUTRITION		TOTAL MADE
tachycardia	1	Snores (OSA)	1	Limited arm raise	1	none	0
abnormal CMRI	1			Walks No stairs	1
				Fatigue improves with rest	1
Domain Points	2	1		3		0		6
18 yo palpitations, HR 120, EF 30%, worsening dyspnea, BIPAP use 24 hours, last forced vital capacity 39%, anorexia, severe fatigue in bed, heart failure hospitalization for diuresis, milrinone
CARDIAC		PULMONARY		MYOPATHY		NUTRITION		TOTAL MADE
tachycardia	1	dyspnea at rest	2	confined to bed	3	anorexia	2
palpitations	2	24hour BIPAP	4	no use of hands	3
EF 30%	4	FVC 39%	3
transient inotropes	3
CHF hospitalization	4
Domain Points	14		9		6		2	31

Abbreviations: CHF congestive heart failure, CMRI cardiac magnetic resonance imaging, DMD Duchenne muscular dystrophy, HR heart rate, echo echocardiog ram, EF ejection fraction, FVC forced vital capacity, ROS review of systems, yo years old