Table 5.

MADE Domain contributions to Total MADE score (effect size) and ambulatory cohorts, adjusting for length of followup and baseline age.

	Ambulatory		Non-ambulatory
MADE Domain	Effect size	P-value	Effect size	P-value
CARDIAC
Years in the study	0.1	<0.001	0.2	<0.001
Baseline age	0.1	<0.001	0.2	<0.001
MYOPATHY
Years in the study	0.5	<0.001	0.09	<0.001
Baseline age	0.3	<0.001	0.07	0.002
NUTRITION
Years in the study	0.02	0.007	−0.0005	0.98
Baseline age	0.08	<0.001	0.1	<0.001
PULMONARY
Years in the study	0.2	<0.001	0.6	<0.001
Baseline age	0.2	<0.001	0.6	<0.001