Table 2.

Summary of reports of severe immediate hypersensitivity to gadolinium contrast agent in the patient with malignance.

Author, year	GBCAs	Gender	Age	Diagnosis	History of allergy
Nomura M, et al, 1993[17]	Gd-DTPA	Female	24	Suprasellar brain tumor	Rhinallergosis
Katoh A, et al, 1993[18]	Gd-DTPA	Female	18	Tuberous sclerosis and renal tumors	Asthma bronchiale
Jordan RM, et al, 1995[19]	Gd-DTPA	Female	67	Suprasellar mass	A history of severe chronic obstructive pulmonary disease
Li A, et al, 2006[20]	Gd-DTPA	Not described	77	Malignant melanoma of the nostril	No
Simons CW, et al, 2009[21]	Gadoteridol	Female	58	Breast cancer and hypertension	No
Kerget B. 2018[22]	Gadobutrol	Female	46	Submandibular mass	No
Moreno Escobosa MC, et al, 2018[23]	Gadobutrol	Male	45	Astrocytoma	Not described
Sellaturay, P, et al, 2018[24]	Gadobutrol	Male	47	Low-grade glioma	No
Malone J, et al, 2020[25]	Gadobutrol	Female	46	Hemangiopericytoma	Allergic to penicillin, sulpha drugs, and dimenhydrinate

GBCAs = gadolinium-based contrast agents, Gd-DTPA = gadopentetate dimeglumine.