Table 3.
Common effects of TC1 and Chibby on the expression β-catenin target gens in LSCC*.
| Groups | n | c-Myc expression | P value | Cyclin D1 expression | P value | MMP-7 expression | P value | |||
|---|---|---|---|---|---|---|---|---|---|---|
| Negative (%) | Positive (%) | Negative (%) | Positive (%) | Negative (%) | Positive (%) | |||||
| TC1+/Chibby− | 25 | 2 (8.00) | 23 (92.00) | 1 (4.00) | 24 (96.00) | 0 (0.00) | 25 (100.00) | |||
| TC1+/Chibby+ | 19 | 4 (21.05) | 15 (78.95) | .339 | 4 (21.05) | 15 (78.95) | <.001 | 2 (10.53) | 17 (89.47) | <.001 |
| TC1-/Chibby− | 3 | 1 (33.33) | 2 (66.67) | 3 (100.00) | 0 (0.00) | 1 (33.33) | 2 (66.67) | |||
| TC1-/Chibby+ | 6 | 2 (33.33) | 4 (66.67) | 4 (66.67) | 2 (33.33) | 6 (100.00) | 0 (0.00) | |||
LSCC = laryngeal squamous cell carcinoma, MMP-7 = matrix metalloproteinase-7, TC1 = thyroid cancer 1.
*
All statistical significance was determined using the Fisher exact test in R × C table because of some theoretical frequency was smaller than 5. The results were showed by number (%). P value of <.05 was considered statistically significant.