Table 4.
Univariate analysis of factors associated with overall survival of patients with LSCC*.
| Variable | Comparison | HR (95%CI) | P value |
|---|---|---|---|
| Sex | Female vs Male | 0.05 (0.00–1699063.23) | .731 |
| Age | ≥66 vs <66 yr | 2.34 (0.45–12.05) | .310 |
| Smoking | Yes vs No | 0.55 (0.12–2.47) | .428 |
| Drinking | Yes vs No | 0.45 (0.10–2.00) | .293 |
| Tumor site | Non-glottic vs Glottic | 3.32 (0.64–17.14) | .151 |
| TNM stage | III + IV vs I + II | 6.81 (0.82–56.85) | .076 |
| T stage | 3 + 4 vs 1 + 2 | 7.82 (0.94–65.25) | .058 |
| Lymphatic metastasis | Yes vs No | 0.88 (0.11–7.28) | .902 |
| Lymphovascular invasion | Yes vs No | 1.93 (0.43–8.62) | .390 |
| Perineurial invasion | Yes vs No | 2.88 (0.54–15.43) | .217 |
| Differentiation | Moderately + Poorly vs Highly | 3.75 (0.45–31.18) | .221 |
| TC1 | Positive vs Negative | 30.10 (0.01–68114.11) | .388 |
| Chibby | Positive vs Negative | 1.46 (0.33–6.55) | .621 |
| β-catenin | Positive vs Negative | 40.98 (0.06–27977.50) | .265 |
| TC1/Chibby | TC1+/Chibby− vs othersa | 0.68 (0.28–1.66) | .392 |
CI = confidence interval, LSCC = laryngeal squamous cell carcinoma, TC1 = thyroid cancer 1, TNM = tumor node metastases.
a
“Others” represented the groups of TC1+/Chibby+, TC1-/Chibby−, and TC1-/Chibby+.
*
All statistical significance was determined using the univariate Cox proportional hazards model. P value of <.05 was considered statistically significant.